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Arthur R. Garan, MD

  • Assistant Professor of Medicine at CUMC
Arthur R. Garan, MD

Arthur Reshad Garan is a cardiologist with specialized training in the treatment of advanced heart failure including those requiring left ventricular assist device or cardiac transplantation. He also has expertise in the care of critically ill patients with cardiac disease. He is board certified in internal medicine, cardiovascular diseases, and advanced heart failure and cardiac transplantation.

Dr. Garan received his medical degree from Columbia University College of Physicians and Surgeons in 2006. He completed internal medicine residency training and cardiology fellowship training at Columbia University Medical Center/NewYork-Presbyterian. He also completed additional fellowship training in advanced heart failure and cardiac transplantation at Columbia University Medical Center/NewYork-Presbyterian. He is currently the Associate Director of the Cardiac Intensive Care Unit and Medical Director of the Acute Circulatory Support Program at the Columbia University Medical Center.

Dr. Garan’s research interest includes treatment of patients with advanced heart failure, cardiogenic shock, and both temporary and long-term circulatory support devices. He is supported by National Institutes of Health Grant No. KL2TR001874. His work has been presented internationally and published in numerous peer-reviewed journals including the Journal of the American College of Cardiology, JACC: Heart Failure, and the Journal of Heart and Lung Transplantation, among others.

Education & Training

  • MD, Columbia University College of Physicians and Surgeons
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: NewYork-Presbyterian/Columbia

Honors & Awards

  • Gold Humanism in Medicine Circle of Excellence 2009, Columbia University
  • Critical Care Resident Award, Department of Medicine, Columbia University
  • Physician of the Year 2016, NY Presbyterian Hospital - Columbia University 
  • Ewig Award for Clinical Education 2017, Department of Medicine, Columbia University

Research Interests

  • Advanced Heart Failure
  • Left Ventricular Assist Devices
  • Cardiogenic Shock

NIH Grants

  • TRANSFORM-HF (TORSEMIDE COMPARISON WITH FUROSEMIDE FOR MANAGEMENT OF HEART FAILURE) STUDY (Federal Gov)

    Aug 1 2018 - Jul 31 2022

    INSTITUTIONAL CAREER DEVELOPMENT CORE (Federal Gov)

    Jul 1 2016 - May 31 2021

Publications

Peer Reviewed Articles

  1. Garan AR, Maron BJ, Wang PJ, Estes NAM, Link MS. Role of Streptomycin-Sensitive Stretch-Activated Channel in Chest Wall Impact Induced Sudden Death (Commotio Cordis). J Cardiovasc Electrophysiol 2005;16:433-8.
  2. Garan A, Al-Ahmad A, Mihilak T, Cartier C, Capuano L, Holtan D, Song C, Homoud MK, Link MS, Estes NAM III, Wang PJ Cryoablation of the Pulmonary Veins Using a Novel Balloon Catheter. J Interv Card Electrophysiol. 2006;15:79-81.
  3. Garan AR, Uriel N, Sayer S, Sims D, Zahner D, Farr M, Mancini D, Jorde U. Alteration in Systemic Vascular Resistance and Cardiac Output During Acute Cellular Rejection and Recovery in Heart Transplant Recipients. J Heart Lung Transplant 2010;29:382-4.
  4. Hirsh BJ, Mignatti A, Garan AR, Uriel N, Colombo PC, Sims DB, Jorde UP. Effect of Beta Blocker Cessation on Chronotropic Incompetence and Exercise Tolerance in Patients with Advanced Heart Failure. Circ Heart Fail 2012;5(5):560-5.
  5. Uriel N, Morrison KA, Garan AR, Kato TS, Yuzefpolskaya M, Latif F, Restaino S, Mancini D, Flannery M, Takayama H, John R, Colombo P, Naka Y, Jorde U. Development of a novel echocardiography ramp test for speed optimization and diagnosis of device thrombosis in continuous flow left ventricular assist devices: The Columbia Ramp Study. J Am Coll Cardiol 2012;60:1764-75.
  6. Garan AR, Yuzefpolskaya M, Colombo PC, Morrow JP, Te-Frey R, Dano D, Takayama H, Naka Y, Garan H, Jorde UP, Uriel N. Ventricular Arrhythmias and ICD therapy in Patients with Continuous Flow Left Ventricular Assist Devices: Need for Primary Prevention? J Am Coll Cardiol 2013;61:2542-50.
  7. Uriel N, Han J, Morrison KA, Nahumi N, Yuzefpolskaya M, Garan AR, Duong J, Colombo PC, Takayama H, Thomas SS, Naka Y, Jorde UP. Device Thrombosis in Heartmate II Continuous-Flow Left Ventricular Assist Devices: A Multifactorial Phenomenon. J Heart Lung Transplant 2014;3:51-9.
  8. Nahumi N, Morrison KA, Garan AR, Uriel N, Jorde UP. Peak Exercise Capacity Is a Poor Indicator of Functional Capacity for Patients Supported by a Continuous Flow Left Ventricular Assist Device. J Heart Lung Transplant 2014;33:213-5.
  9. Morrison KA, Jorde UP, Garan AR, Naka Y, Uriel N. Acquired von Willebrand Disease During CentriMag Support Is Associated with High Prevalence of Bleeding During Support and after Transition to Heart Replacement Therapy. ASAIO J 2014;60-241-2.
  10. Garan AR, Iyer V, Whang W, Mody K, Yuzefpolskaya M, Colombo PC, Te-Frey R, Takayama H, Naka Y, Garan H, Jorde UP, Uriel N. Catheter Ablation for Ventricular Tachyarrhythmias in Patients Supported by Continuous Flow Left Ventricular Assist Device. ASAIO J. 2014;60:311-6.
  11. Uriel N, Nahumi N, Colombo PC, Yuzefpolskaya M, Restaino SW, Han J, Thomas SS, Garan AR, Takayama H, Mancini DM, Naka Y, Jorde UP. Advanced heart failure in patients infected with human immunodeficiency virus: Is there equal access to care? J Heart Lung Transplant. 2014;33:924-30.
  12. Fried J, Levin AP, Mody KP, Garan AR, Yuzefpolskaya M, Takayama H, Diuguid DL, Naka Y, Jorde UP, Uriel N. Prior Hematological Conditions Carry a High Morbidity and Mortality in Patients Supported with Continuous Flow Left Ventricular Assist Devices. J Heart Lung Transplant 2014;33:1119-25.
  13. Levin AP, Uriel N, Takayama H, Mody K, Ota T, Yuzefpolskaya M, Colombo P, Garan A, Dionizovik-Dimanovski M, Sladen R, Naka Y, Jorde U.. Device exchange in Heartmate II recipients: long-term outcomes and risk of thrombosis recurrence. ASAIO J 2014. Epub ahead of print.
  14. Dionizovik-Dimanovski M, Levin AP, Fried J, Mody KP, Simonich E, Garan AR, Yuzefpolskaya M, Takayama H, Naka N, Colombo PC, Kalesan B, Uriel N, Jorde UP. Correlation between home INR and core lab INR in patients supported with continuous-flow left ventricular assist devices. ASAIO J 2015;61:386-90.
  15. Uriel N, Levin AP, Sayer GT, Mody KP, Thomas SS, Adataya S, Yuzefpolskaya M, Garan AR, Breskin A, Takayama H, Colombo PC, Naka Y, Burkhoff D, Jorde UP. Left ventricular decompression during speed optimization ramps in patients supported by CF-LVADs: device specific performance characteristics and impact on diagnostic algorithms. J Card Fail 2015;21:785-91.
  16. Garan AR, Levin AP, Topkara VK, Thomas SS, Yuzefpolskaya M, Colombo PC, Takeda K, Takayama H, Naka Y, Whang W, Jorde UP, Uriel N. Early Post-Operative Ventricular Arrhythmias in Patients with Continuous Flow Left Ventricular Assist Devices. J Heart Lung Transplant 2015;34:1611-6.
  17. Tsukashita M, Takayama H, Takeda K, Han J, Colombo PC, Yuzefpolskaya M, Topkara VK, Garan AR, Mancini DM, Kurlansky PA, Naka Y. Effect of pulmonary vascular resistance before left ventricular assist device implantation on short- and long-term post-transplant survival. J Thorac Cardiovasc Surg 2015;150:1352-61.
  18. Pan S, Aksut B, Wever-Pinzon OE, Rao SD, Levin AP, Garan AR, Fried JA, Takeda K, Takayama H, Yuzefpolskaya M, Uriel N, Jorde UP, Mancini M, Naka Y, Colombo PC, Topkara VK. Incidence and Predictors of Myocardial Recovery on Continuous-Flow Left Ventricular Assist Device Support: Results from the United Network Organ Sharing Database. J Heart Lung Transplant 2015;34:1624-9.
  19. Han J, Takeda K, Truby L, Fukuhara S, Mauro C, Kurlansky P, Yuzefpolskaya M, Topkara V, Garan AR, Colombo PC, Mancini DM, Takayama H, Naka Y. Durability and clinical impact of tricuspid valve procedures in patients receiving continuous-flow left ventricular assist device. J Thorac Cardiovasc Surg 2015;151:520-7.
  20. Cagliostro B, Levin AP, Fried J, Stewart S, Parkis G, Mody KP, Garan AR, Topkara V, Takayama H, Naka Y, Jorde UP, Uriel N. Continuous-Flow Left Ventricular Assist Devices and Usefulness of a Standardized Strategy to Reduce Driveline Infections. J Heart Lung Transplant 2015;35:108-14.
  21. Levin AP, Jaramillo N, Garan AR, Takeda K, Takayama H, Yuzefpolskaya M, Mancini DM, Naka Y, Colombo PC, Topkara, VK. Outcomes of contemporary mechanical circulatory support device configurations in patients with severe biventricular failure. J Thorac Cardiovasc Surg 2016;151:520-7.
  22. Wever-Pinzon O, Pan S, Garan AR, Takeda K, Takayama H, Naka Y, Mancini D, Colombo P, Topkara VK. National Trends and Outcomes in Device-Related Thromboembolic Complications and Malfunction Among Heart Transplant Candidates Supported With Continuous-Flow Left Ventricular Assist Devices in the United States. J Heart Lung Transplant 2016;35:884-92.
  23. Hickey KT, Garan H, Mancini DM, Colombo PC, Naka Y, Sciacca RR, Abrams MP, Solove M, Zeoli N, Flannery M, Garan AR, Biviano AB. Atrial Fibrillation in Patients With Left Ventricular Assist Devices: Incidence, Predictors, and Clinical Outcomes. JACC: Electrophysiol 2016. Epub ahead of print.
  24. Topkara VK, Knotts RJ, Jennings DL, Garan AR, Levin AP, Breskin A, Castagna F, Cagliostro B, Yuzefpolskaya M, Takeda K, Takayama H, Uriel N, Mancini DM, Eisenberger A, Naka Y, Colombo PC, Jorde UP. Effect of CYP2C9 and VKORC1 Gene Variants on Warfarin Response in Patients with Continuous-Flow Left Ventricular Assist Devices (CF-LVADs). ASAIO J. 2016;62:558-64.
  25. Willey JZ, Gavalas MV, Trinh PN, Yuzefpolskaya M, Garan AR, Levin AP, Takeda K, Takayama H, Fried J, Naka Y, Colombo PC. Outcomes after stroke complicating left ventricular assist device. J Heart Lung Transplant. 2016;35:1003-9.
  26. Topkara VK, Garan AR, Fine B, Godier-Furnémont AF, Breskin A, Cagliostro B, Yuzefpolskaya M, Takeda K, Takayama H, Mancini DM, Naka Y, Colombo PC. Myocardial Recovery in Patients Receiving Contemporary Left Ventricular Assist Devices: Results from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS). Circ Heart Failure. Epub ahead of print.
  27. Gavalas M, Breskin A, Yuzefpolskaya M, Eisenberger A, Castagna F, Demmer RT, Flannery M, Garan AR, Takeda K, Takayama H, Naka Y, Topkara VK, Colombo PC. Discriminatory performance of positive urine hemoglobin for detection of significant hemolysis in CF-LVAD patients. J Heart Lung Transplant 2017;36:59-63.
  28. Clerkin KJ, Garan AR, Wayda B, Givens RC, Yuzefpolskaya M, Nakagawa S, Takeda K, Takayama H, Naka Y, Mancini DM, Colombo PC, Topkara VK. The impact of socioeconomic status on patients supported with a left ventricular assist device: an analysis of the UNOS database. Circ Heart Fail 2016; Epub ahead of print.
  29. Takeda K, Garan AR, Topkara VK, Kirtane AJ, Karmpaliotis D, Kurlansky P, Yuzefploskaya M, Colombo PC, Naka Y, Takayama H. Novel minimally invasive surgical approach using an external ventricular assist device and extracorporeal membrane oxygenation in refractory cardiogenic shock. Eur J Cardiothorac Surg 2016; Epub ahead of print.
  30. Topkara VK, Coromilas EJ, Garan AR, Li RC, Castagna F, Jennings DL, Yuzefpolskaya M, Takeda K, Takayama H, Sladen RN, Mancini DM, Naka Y, Radhakrishnan J, Colombo PC. Pre-operative proteinuria and reduced glomerular filtration rate predicts renal replacement therapy in patients supported with continuous-flow left ventricular assist devices. Circ Heart Fail 2016; Epub ahead of print.
  31. Clerkin KJ, Topkara VK, Mancini DM, Yuzefpolskaya M, Demmer RT, Dizon J, Takeda K, Takayama H, Naka Y, Colombo PC, Garan AR. The Role of Implantable Cardioverter Defibrillators in Patients Bridged to Transplantation with a Continuous Flow Left Ventricular Assist Device: A Propensity Score Matched Analysis. J Heart Lung Transplant 2016. Epub ahead of print.
  32. Takeda K, Han J, Garan AR, Topkara VK, Kurlansky P, Yuzefploskaya M, Colombo PC, Naka Y, Takayama H. Changes in end-organ function in patients with prolonged continuous-flow LVAD support. Ann Thorac Surg 2016. Epub ahead of print.
  33. Takeda K, Li B, Garan AR, Topkara VK, Han J, Colombo PC, Farr MA, Naka Y, Takayama H. Improved outcomes from extracorporeal membrane oxygenation versus ventricular assist device temporary support of primary graft dysfunction in heart transplant. J Heart Lung Transplant 2016. Epub ahead of print.
  34. Yoshioka D, Takayama H, Garan AR, Topkara VK, Han J, Li B, Kurlansky P, Yuzefpolskaya M, Colombo PC, Naka Y, Takeda K. Bridge to durable left ventricular assist device for refractory cardiogenic shock. J Thorac Cardiovasc Surg. 2016. Epub ahead of print.
  35. Yoshioka D, Takayama H, Colombo PC, Yuzefpolskaya M, Garan AR, Topkara VK, Han J, Kurlansky P, Naka Y, Takeda K. Changes in End-Organ Function in Patients With Prolonged Continuous-Flow Left Ventricular Assist Device Support. Ann Thorac Surg 2017;10:717-724.
  36. Fujita K, Takeda K, Li B, Mauro C, Kurlansky P, Sreekanth S, Han J, Truby LK, Garan AR, Topkara V, Yuzefpolskaya M, Colombo P, Naka Y, Takayama H. Combined Therapy of Ventricular Assist Device and Membrane Oxygenator for Profound Acute Cardiopulmonary Failure. ASAIO J. Epub ahead of print.
  37. Yoshioka D, Takayama H, Garan AR, Topkara VK, Han J, Kurlansky P, Yuzefpolskaya M, Colombo PC, Naka Y, Takeda K. Contemporary outcome of unplanned right ventricular assist device for severe right heart failure after continuous-flow left ventricular assist device insertion. Interact Cardiovasc Thorac Surg 2017. Epub ahead of print.
  38. Castagna F, McDonnell BJ, Stöhr EJ, Yuzefpolskaya M, Trinh PN, Topkara VK, Garan AR, Flannery MA, Takeda K, Takayama H, Naka Y, Demmer RT, Wassertheurer S, Cockcroft J, Colombo PC. Non-invasive measurement of peripheral, central and 24-hour blood pressure in patients with continuous-flow left ventricular assist device. J Heart Lung Transplant. 2017. Epub ahead of print.
  39. Truby LK, Takeda K, Mauro C, Yuzefpolskaya M, Garan AR, Kirtane AJ, Topkara V, Abrams D, Brodie D, Colombo PC, Naka Y, Takayama H. Incidence and Implications of Left Ventricular Distention During Venoarterial Extracorporeal Membrane Oxygenation Support. ASAIO J. 2017. Epub ahead of print.
  40. Abadeer AI, Kurlansky P, Chiuzan C, Truby L, Radhakrishnan J, Garan R, Topkara V, Yuzefpolskaya M, Colombo P, Takeda K, Naka Y, Takayama. Importance of stratifying acute kidney injury in cardiogenic shock resuscitated with mechanical circulatory support therapy. J Thorac Cardiovasc Surg. 2017. Epub ahead of print.
  41. Wright M, Takeda K, Mauro C, Jennings D, Kurlansky P, Han J, Truby L, Stein S, Topkara V, Garan AR, Yuzefpolskaya M, Colombo P, Naka Y, Farr M, Takayama H. Dose-dependent association between amiodarone and severe primary graft dysfunction in orthotopic heart transplantation. J Heart Lung Transplant. 2017. Epub ahead of print.
  42. Takeda K, Garan AR, Ando M, Han J, Topkara VK, Kurlansky P, Yuzefpolskaya M, Farr MA, Colombo PC, Naka Y, Takayama H. Minimally invasive CentriMag ventricular assist device support integrated with extracorporeal membrane oxygenation in cardiogenic shock patients: a comparison with conventional CentriMag biventricular support configuration. Eur J Cardiothorac Surg. 2017. Epub ahead of print.
  43. Salna M, Takayama H, Garan AR, Kurlansky P, Farr MA, Colombo PC, Imahiyerobo T, Morrissey N, Naka Y, Takeda K. Incidence and risk factors of groin lymphocele formation after venoarterial extracorporeal membrane oxygenation in cardiogenic shock patients. J Vasc Surg. 2017. Epub ahead of print.
  44. Clerkin KJ, Topkara VK, Mancini DM, Fried JA, Yuzefpolskaya M, Demmer RT, Dizon JM, Takeda K, Takayama H, Naka N, Colombo PC, Garan AR. Implantable Cardioverter Defibrillators in Patients with a Continuous Flow Left Ventricular Assist Device: An Analysis of the INTERMACS Registry. JACC: Heart Fail 2017. Epub ahead of print.

Abstracts and Presentations

  1. Garan A, Mihilak T, Cartier C, Capuano L, Holtan D, Song C, Homoud MK, Link MS, Estes NAM III, Wang PJ. Cryoablation of the Pulmonary Veins Using a Novel Balloon Catheter.  The American College of Cardiology, Chicago, Illinois, April, 2003.
  2. Garan AR, Kolluri S, Lombardo I, Maurer MS. The prevalence of Holter Abnormalities in ATTR Cardiac Amyloidosis. The International Symposium on Amyloidosis, Groningen, Netherlands, May, 2012.
  3. Garan AR, Morrison K, Letarte L, Vazquez J, Dano D, Colombo PC, Yuzefpolskaya M, Te-Frey R, Takayama H, Naka Y, Morrow J, Garan H, Jorde UP, Uriel N. Ventricular Arrhythmias in Patients Following Continuous Flow Left Ventricular Assist Device Implantation. The American Heart Association Scientific Sessions, Los Angeles, November, 2012.
  4. Garan AR, Maurer MS, Suhr OB, Mundayat R. Pacemaker Use in Patients with Transthyretin Amyloidosis in THAOS—The Transthyretin Amyloidosis Survey. The American College of Cardiology, San Francisco, 2013.
  5. Garan AR, Nahumi N, Han J, Colombo P, Yuzefpolskaya M, Te-Frey R, Takayama H, Naka Y, Uriel N, Jorde UP. Chronotropic Incompetence in Patients Supported by Left Ventricular Assist Device. The International Society for Heart & Lung Transplantation, Montreal, April, 2013.
  6. Garan AR, Han J, Nahumi N, Yuzefpolskaya M, Colombo P, Whang W, Morrow J, Garan H, Jorde UP, Uriel N. Catheter Ablation of Ventricular Arrhythmias in Patients Supported by Left Ventricular Assist Device. The International Society for Heart & Lung Transplantation, Montreal, April, 2013.
  7. Garan AR, Morrison K, Letarte L, Vazquez J, Dano D, Colombo PC, Yuzefpolskaya M, Te-Frey R, Takayama H, Naka Y, Morrow J, Garan H, Jorde UP, Uriel N. Ventricular Arrhythmias in Patients Following Continuous Flow Left Ventricular Assist Device Implantation. The International Society for Heart & Lung Transplantation, Montreal, April, 2013. 
  8. Garan AR, Levin AP, Mody KP, Rao S, Dionizovik-Dimanovski M, Colombo PC, Yuzefpolskaya M, Takayama H, Naka Y, Restaino S, Mancini D, Uriel N, Jorde UP. Continuous Flow LVAD Support and Immune Suppression. The International Society for Heart & Lung Transplantation, San Diego, April, 2014.
  9. Garan AR, Mody KP, Levin AP, Fried J, Dionizovik-Dimanovski M, Yuzefpolskaya M, Colombo PC, Takayama H, Naka Y, Restaino S, Mancini D, Jorde UP, Uriel N. Atrial Fibrillation in Patients Supported by Continuous-Flow Left Ventricular Assist Device. The International Society for Heart & Lung Transplantation, San Diego, April, 2014.
  10. Garan AR, Mai X, Levin AP, Topkara VK, Thomas SS, Yuzefpolskaya M, Colombo PC, Mancini M, Takeda K, Takayama H, Naka Y, Jorde UP, Uriel N. The Use of Cardiac Resynchronization Therapy in Patients with Left Ventricular Assist Device. The International Society for Heart & Lung Transplantation, Nice, France, April, 2015.
  11. Garan AR, Whang W, Topkara VK, Levin AP, Yuzefpolskaya M, Colombo PC, Mancini M, Takeda K, Takayama H, Naka Y, Uriel N, Jorde UP. The Timing and Location of Intractable Ventricular Arrhythmias Following Left Ventricular Assist Device Implantation. The International Society for Heart & Lung Transplantation, Nice, France, April, 2015. 

For a complete list of publications, please visit PubMed.gov