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Elizabeth C. Verna, MD

  • Assistant Professor of Medicine at CUMC
Elizabeth C. Verna, MD

Dr. Elizabeth C. Verna manages patients with a variety of liver diseases. Her clinical interests focus on viral hepatitis and liver transplantation as well as the new emerging therapies for hepatitis C, liver cancer, alcoholic and non-alcoholic fatty liver disease and metabolic liver diseases. She also has expertise in the management of end stage liver disease and its complications.

Active research program with grant support for the study of hepatitis C in liver transplant recipients and will be actively involved in clinical trials forthe treatment of hepatitis C in both the transplant and non-transplant settings.

Education & Training

  • Columbia University College of Physicians and Surgeons
  • Residency: NewYork-Presbyterian/Columbia
  • Fellowship: NewYork-Presbyterian/Columbia

Committees / Societies / Memberships

  • American Society of Transplantation
  • American Association for the Study of Liver Diseases. 2011 Training and Clinical Policy Committee Member
  • American Gastroenterological Association

Grants

  • 2011-2013 National Institutes of Health K12 Career Development Award, Columbia University College of Physicians and Surgeons
  • 2011-2013 American Association for the Study of Liver Diseases Sheila Sherlock Clinical and Translational Research Award, Columbia University College of Physicians and Surgeons
  • 2010-2011 American College of Gastroenterology Clinical Research Award
  • Columbia University College of Physicians and Surgeons
  • 2010-2011 American Association for the Study of Liver Diseases Advanced/Transplant Hepatology
  • Fellowship Award, Columbia University College of Physicians and Surgeons
  • 2010-2011 Glenda Garvey Teaching Academy Award (Co-Investigator) for "Women in 3D" and alcohol awareness initiative targeting young women, Columbia University College of Physicians and Surgeons
  • 2009-2010 National Institutes of Health T32 Training Grant
  • Columbia University College of Physicians and Surgeons
  • 2008-2010 Patient Oriented Research Scholarship for a Masters in Biostatistics
  • Columbia University Mailman School of Public Health

NIH Grants

  • PREDICTING POST-TRANSPLANT MORTALITY AND GLOBAL FUNCTIONAL HEALTH BASED ON PRE-TRANSPLANT FUNCTIONAL STATUS IN LIVER TRANSPLANTATION (Federal Gov)

    Jun 15 2018 - May 31 2023

    A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF EMRICASAN, AN ORAL CASPASE INHIBITOR, IN SUBJECTS WITH DECOMPENSATED NON-ALCOHOLIC STEATOHEPATITIS (NASH) CIRRHOSIS (P&S Industry Clinical Trial)

    Feb 2 2018 - Feb 2 2023

    A 5-YEAR LONGITUDINAL OBSERVATIONAL STUDY OF THE NATURAL HISTORY AND MANAGEMENT OF PATIENTS WITH HEPATOCELLULAR CARCINOMA (P&S Industry Clinical Trial)

    Sep 21 2017 - Sep 21 2022

    A MULTICENTER, OPEN-LABEL STUDY TO EVALUATE THE EFFICACY AND SAFETY OF GLECAPREVIR/PIBRENTASVIR IN RENALLY-IMPAIRED ADULTS WITH CHRONIC HEPATITIS C VIRUS GENOTYPE 1 ? 6 INFECTION (EXPEDITION-5) (P&S Industry Clinical Trial)

    Aug 14 2017 - Aug 14 2022

    AN OPEN-LABEL STUDY TO EVALUATE THE SAFETY AND EFFICACY OF SOFOSBUVIR/VELPATASVIR/VOXILAPREVIR FIXED-DOSE COMBINATION FOR 12 WEEKS IN SUBJECTS WHO PARTICIPATED IN A PRIOR GILEAD-SPONSORED HCV TREATMENT STUDY (P&S Industry Clinical Trial)

    Aug 14 2017 - Aug 14 2022

    A 5-YEAR LONGITUDINAL OBSERVATIONAL STUDY OF PATIENTS WITH NONALCOHOLIC FATTY LIVER (NAFL) OR NONALCOHOLIC STEATOHEPATITIS (NASH) (P&S Industry Clinical Trial)

    Aug 3 2017 - Aug 3 2022

    A RANDOMIZED, DOUBLE-BLIND, MULTI-DOSE, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF GSK2330672 ADMINISTRATION FOR THE TREATMENT OF PRURITUS IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS. (P&S Industry Clinical Trial)

    Jul 19 2017 - Jul 19 2022

    A 5-YEAR LONGITUDINAL OBSERVATIONAL STUDY OF PATIENTS WITH PRIMARY BILIARY CHOLANGITIS (P&S Industry Clinical Trial)

    Apr 5 2017 - Apr 5 2022

    A MULTICENTER, OPEN-LABEL STUDY OF HARVONI? (SOFOSBUVIR LEDIPASVIR FIXED DOSE COMBINATION) IN SUBJECTS INFECTED WITH CHRONIC HEPATITIS C AND ADVANCED HEART FAILURE OR LUNG DISEASE (P&S Industry Clinical Trial)

    Mar 6 2017 - Mar 6 2022

    THE PRIORITIZE STUDY: A PRAGMATIC, RANDOMIZED STUDY OF ORAL REGIMENS FOR HEPATITIS C: TRANSFORMING DECISION-MAKING FOR PATIENTS, PROVIDERS, AND STAKEHOLDERS. (Private)

    Mar 1 2016 - Feb 28 2021

    TCR AND BCR DEEP SEQUENCING TO DISTINGUISH AUTOIMMUNE RECURRENCE FROM ALLOGRAFT REJECTION (Federal Gov)

    Aug 1 2018 - Jul 31 2020

    AN OPEN-LABEL, MULTI-CENTER STUDY TO EVALUATE THE LONG-TERM OUTCOMES FOLLOWING TREATMENT WITH ABT-450/RITONAR / ABT-267 (ABT-450/R/ABT-267) AND ABT-333 WITH OR WITHOUT RIBAVIRIN (RBV) IN ADULTS WITH GENOTYPE 1 CHRONIC HEPATITIS C VIRUS (HCV) (P&S Industry Clinical Trial)

    Sep 12 2014 - Sep 12 2019

    BACTERIAL TRANSLOCATION AND THE INTESTINAL MICROBIOME IN RECURRENT DISEASE FOLLOWING LIVER TRANSPLANTATION (Federal Gov)

    Sep 1 2015 - Aug 31 2019

    A MULTICENTER, DOUBLE-BLIND, SPONSOR-OPEN TRIAL OF IDN-6556 IN SUBJECTS WHO HAD HEPATITIS C VIRUS (HCV) REINFECTION AND LIVER FIBROSIS FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION FOR CHRONIC HCV INFECTION (P&S Industry Clinical Trial)

    Jul 24 2014 - Jul 24 2019

    A PHASE II/III CLINICAL TRIAL TO STUDY THE EFFICACY AND SAFETY OF THE COMBINATION REGIMEN OF MK-5172 AND MK-8742 IN SUBJECTS WITH CHRONIC HEPATITIS C VIRUS INFECTION WITH ADVANCED CIRRHOSIS AND CHILD-PUGH (P&S Industry Clinical Trial)

    Jun 19 2014 - Jun 19 2019

    A PHASE II/III RANDOMIZED CLINICAL TRIAL TO STUDY THE EFFICACY AND SAFETY OF THE COMBINATION REGIMEN OF MK-5172 AND MK-8742 IN SUBJECTS WITH CHRONIC HEPATITIS C VIRUS INFECTION AND CHRONIC KIDNEY DISEASE (P&S Industry Clinical Trial)

    Apr 17 2014 - Apr 17 2019

    PROSPECTIVE, SINGLE-CENTER, OPEN LABEL, PILOT STUDY OF SAFETY AND EFFICACY OF TRIPLE ANTI-VIRAL THERAPY WITH PEGYLATED INTERFERON, RIBAVIRIN, AND BOCEPREVIR IN PATIENTS WITH GENOTYPE 1 CHRONIC HCV WITH END STAGE RENAL DISEASE (P&S Industry Clinical Trial)

    Dec 23 2013 - Dec 23 2018

    A MULTICENTER, RANDOMIZED, PROSPECTIVE, OPEN-LABEL PHASE III STUDY TO EVALUATE THE EFFICACY, SAFETY AND PHARMACOKINETICS OF HEPATITIS C IMMUNE GLOBULIN INTRAVENOUS (P&S Industry Clinical Trial)

    Aug 15 2013 - Aug 15 2018

    MOLECULAR SUBTYPES FOR TARGETED THERAPIES IN ALCOHOLIC HEPATITIS (Federal Gov)

    Sep 1 2017 - May 31 2018

    A PHASE 3B, MULTI-CENTER, RANDOMIZED, OPEN-LABEL, PRAGMATIC STUDY OF GLECAPREVIR/PIBRENTASVIR (G/P) +/- RIBAVIRIN FOR GT1 SUBJECTS WITH CHRONIC HEPATITIS C PREVIOUSLY TREATED WITH AN NS5A INHIBITOR + SOFOSBUVIR THERAPY (P&S Industry Clinical Trial)

    Aug 14 2017 - Aug 14 2017

    INTEGRATED APPROACHES FOR IDENTIFYING MOLECULAR TARGETS IN ALCOHOLIC HEPATITIS (Federal Gov)

    Jun 1 2013 - May 31 2017

    INTEGRATED APPROACHES FOR IDENTIFYING MOLECULAR TARGETS IN ALCOHOLIC HEPATITIS (Federal Gov)

    Jun 1 2013 - Apr 30 2017

    CLINICAL AND TRANSLATIONAL SCIENCE AWARD (KL2) (Federal Gov)

    Sep 30 2006 - Jun 30 2016

    CLINICAL AND TRANSLATIONAL SCIENCE AWARD (KL2) (Federal Gov)

    Sep 30 2006 - Jun 30 2016

    INTEGRATED APPROACHES FOR IDENTIFYING MOLECULAR TARGETS IN ALCOHOLIC HEPATITIS (Federal Gov)

    Jun 1 2013 - May 31 2016

    FRAILTY AND FUNCTIONAL STATUS IN OLDER LIVER TRANSPLANT PATIENTS (Federal Gov)

    Sep 1 2015 - Apr 30 2016

Publications

Peer Reviewed Publications

  • Verna EC, Ferrand E, Pichardo EM, Balducci A, Emond JC, Guarrera J, Brown RS. “Basiliximab
  • Induction and Delayed Calcineurin Inhibitor Initiation in Liver Transplant Recipients with Renal
  • Failure.” Transplantation, In press.
  • Lai JC, Verna EC, Brown RS, O-Leary J, Trotter J, Forman LM, Dunman J, Foster RG, Stravitz RT,
  • Terrault NA. “Hepatitis C Virus Infected Females are at a Higher Risk of Advanced Firbosis and
  • Graft Loss after Liver Transplantation: From the CRUSH-C Consortium.” Hepatology, In press.
  • Chang MS, Shah JP, Amin S, Gonzalez, S, Prowda JC, Cheng JM, Verna EC, Rockey DC, Frucht H.
  • “Physician Knowledge and Appropriate Utilization of Computer Tomographic Colonography in
  • Colorectal Cancer Screening.” Abdomin Imaging, In press.
  • Rossi ED, Larghi A, Verna EC, Martini M, Galasso D, Carnuccio A, Larocca LM, Costamagna G, Fadda G.”
  • Endoscopic ultrasound-guided fine-needle aspiration with liquid-based cytologic preparation in the
  • diagnosis of primary pancreatic lymphoma.” Pancreas, 2010 Nov;39(8):1299-302.
  • Verna EC, Stevens PD, Hwang C, Stavropoulos S, Sy C, Fine R, Chabot JA, Frucht H. “Pancreatic
  • Cancer Screening in a Prospective Cohort of High Risk Patients: A Comprehensive Strategy of
  • Genetics and Imaging.” Clinical Cancer Res 2010, 15;16(20):5028-37.
  • Verna EC, De Martin E, Gaglio PJ, Burra P, Emond JC, Brown RS. “The Impact of Hepatitis C and
  • Biliary Complications on Patient and Graft Survival Following Liver Transplantation.” Am J
  • Transplant May 2009;9(6):1398-405.Elizabeth Verna - Curriculum Vitae 3
  • Verna EC, Hunt KH, Rudow DL, Hafliger A, Dove LM, Kinkhabwala M, Emond JC, Brown RS.
  • “Predictors of Candidate Maturation Among Potential Living Donors.” Am J Transplant. 2005
  • Oct; 5: 2549-54.
  • Stavropoulos SN, Larghi A, Verna EC, Battezzati PM, Stevens PD. “Intraductal Ultrasound for the
  • Evaluation of Patients with Biliary Strictures and No Abdominal Mass on Computed
  • Tomography.” Endoscopy 2005 Aug;37(8):715-21.
  • Stavropoulos SN, Larghi A, Verna EC, Stevens PD. “Therapeutic ERCP Without Fluoroscopy in
  • Critically Ill Patients Using Wire-Guided Intraductal Ultrasound.” Endoscopy 2005
  • Apr;37(4):389-92.
  • Larghi A, Verna EC, Stavropoulos SN, Rotterdam H, Lightdale CJ, Stevens PD. “EUS-Guided
  • Trucut Needle Biopsies in Patients With Solid Pancreatic Masses: a Prospective Study.”
  • Gastrointest Endosc 2004 Feb;59(2):185-90.

Chapters, Reviews, and Editorials

  • Verna EC, Brown RS “The Use of HCV Positive Organs in Patients With and Without HCV”, Edited by
  • Shiffman M, “Chronic Heptitis C Virus: Lessons from the Past, Promises for the Future,” Springer
  • Publishing, In Press.
  • Verna EC “Hepatitis C Virus”, Edited by Brown RS, “Common Liver Diseases and Transplantation: An
  • Algorithmic Approach to Work-up and Management”, Slack Inc., In Press.
  • Oliver J, Verna EC. “Afferent Mechanisms of Sodium Retention in Cirrhosis and Hepatorenal
  • Syndrome.” Kidney International, 2010;77(8):669-80.
  • Verna EC, Brown RS. “Hepatitis C and Liver Transplantation.” www.uptodate.com.
  • Verna EC, Lucak S. “Use of Probiotics in Gastrointestinal Disorders: What to Recommend.”
  • Therapeutic Advances in Gastroenterology, 2010; 3: 307-319.
  • Verna EC, Brown RS. “HCV and HIV Coinfection Emerging as an Important Clinical Problem.”
  • Gastroenterology and Hepatology News, October, 2009.
  • Verna EC, Larghi A. “Endoscopic Submucosal Dissection: Learning from the Japanese Experience.”
  • Dig Liver Dis 2009;41(3):210-1.
  • Larghi A, Verna EC, Lecca PG, Del Chiaro M, Costamagna G. “Screening for Pancreatic Cancer in
  • High Risk Individuals: A Call for Endoscopic Ultrasound.” Clinical Cancer Res 2009;15:1907-
  • 1914.
  • Verna EC. “Indications for Use of TIPS in Treating Portal Hypertension.” American Medical
  • Association Virtual Mentor. December 2008, Volume 10, Number 12:805-809.
  • http://virtualmentor.ama-assn.org/2008/12/cprl1-0812.html. Accessed Dec. 1, 2008.
  • Verna EC, Burke PD. “Role of Fatty Acids in the Pathogenesis of Obesity and Fatty Liver: Impact
  • of Bariatric Surgery” Seminars Liver Dis. 2008;28:407-26.Elizabeth Verna - Curriculum Vitae 4
  • Verna EC, Dhar V. “Endoscopic Ultrasound-guided Fine Needle Injection for Cancer Therapy: The
  • Evolving Role of Therapeutic Endoscopic Ultrasound.” Therapeutic Advances in
  • Gastroenterology 2008;1:103-109.
  • Verna EC, Brown RS. “Hepatitis C and Liver Transplantation: Enhancing Outcomes and Should
  • They Be Re-transplanted.” Clin Liver Dis, 2008;12:637-659.
  • Verna EC, Brown RS. “Hepatitis C and Liver Transplantation.” Clin Liver Dis 2006;10:919-940.
  • Stevens PD, Verna EC, Lightdale CJ. “Endoscopic Ultrasound of the Biliary Tract.”, Edited by
  • Blumgart L and Fong Y, “Surgery of the Liver and Biliary Tract”, Elsevier Inc., 2006.
  • Verna EC, Larghi A. “How Effective is Endoscopic Ultrasound-Guided Biopsy?” Nat Clin Pract
  • Gastroenterol Hepatol 2006;3(4):200-1.
  • Sharaf RN, Verna EC, Green PD. “Commentary: The International Face of Celiac Disease.”
  • Digestive Liver Dis 2004;36(11):712-3.
  • Frucht H, Stevens PD, Fogelman DR, Verna EC, Chen J, Chabot JA, Fine RL. “Advances in the
  • Genetic Screening, Work-up and Treatment of Pancreatic Cancer.” Curr Treat Options
  • Gastroenterol 2004;7(5):343-354.