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Fangming Lin, MD, PhD

  • Associate Professor of Pediatrics
  • Chief, Division of Pediatric Nephrology
Fangming Lin, MD, PhD

Dr. Fangming Lin joined CUMC in June 2011 as the Division Director of Pediatric Nephrology after 10 years of serving University of Texas Southwestern Medical Center at Dallas. She received her MD degree from Fujian Medical University in China and her PhD degree in Pharmacology at New York Medical College. Dr. Lin underwent pediatric residency training at New York University Medical Center and pediatric nephrology fellowship training at Seattle Children’s Hospital of the University of Washington.

As a physician scientist, Dr. Lin has a strong interest in both patient care and science and discovery. She is passionate and experienced in treating children with congenital kidney conditions as well as acquired kidney diseases. Her laboratory research focuses on the understanding and better treatment for acute and chronic kidney disease. She is the first recipient of the Norman Siegel Pediatric Research Grant Award jointly issued by the American Society of Nephrology (ASN) and the American Society of Pediatric Nephrology (ASPN) in 2006 - a humbling selection of which she is proud. Dr. Lin has also served on several committees at the national and international levels.

Email: fl2300@cumc.columbia.edu

Our laboratory studies kidney injury and repair using a variety of mouse models. We are currently focusing on the function and molecular regulation of epithelial autophagy. We have shown that following urinary tract obstruction or ischemic injury to the kidney, autophagy is activated in a regulated and dynamic fashion for renal tubular survival and repair. A stress-responsive transcription factor FoxO3 plays an important role in regulating the stress response during the acute injury and the progression to chronic kidney disease. Our goal is to use the knowledge learned from animal studies to help design methods that integrate modulation of autophagy into prevention and treatment for human kidney disease.

Education & Training

  • Fujian Medical University (China)
  • Internship: New York University Medical Center
  • Residency: New York University Medical Center
  • Fellowship: Seattle Children's Hospital

Contact Info

NIH Grants

  • ROLE OF AUTOPHAGY IN MALADAPTIVE RENAL REPAIR FOLLOWING ACUTE KIDNEY INJURY (Federal Gov)

    Sep 21 2016 - Aug 31 2019

    PSDP FELLOWSHIP (Federal Gov)

    Jul 1 2018 - Jun 30 2019

    ADVANCING CLINICAL RESEARCH IN PRIMARY GLOMERULAR DISEASES (Federal Gov)

    Sep 16 2013 - May 31 2019

    STEM CELL THERAPY FOR ACUTE KIDNEY INJURY (Federal Gov)

    Jun 1 2011 - Jul 31 2015

    ROLE OF AUTOPHAGY IN KIDNEY TUBULAR ATROPHY (Private)

    Jun 1 2011 - May 31 2014