Jean C. Emond, MD
- Thomas S. Zimmer Professor of Reconstructive Surgery (in Pediatrics)
- Vice Chair, Department of Surgery
- Chief of Transplantation
- Executive Director, Transplant Initiative, NewYork-Presbyterian/Columbia
- Program Director, Transplant & Hepatobiliary Surgery Fellowship
Dr. Emond is the Vice Chairman of Surgery and Chief of the Transplantation Services at Columbia University. He has over30 years of experience performing liver transplantation and complex liver and biliary surgery in children and adults, including the first living donor liver transplantation (LDLT) in the United States. Dr. Emond has published extensively in this field and was a co-chair of the NIH A2ALL program for 13 years. In collaboration with the department of Medicine at Columbia, Dr. Emond recruited the leadership of the Columbia Center for Translational immunology that created the foundation for translational and clinical research in transplantation tolerance. This will lead the way to inducing transplant tolerance in liver patients with the mixed chimerism strategy. As Director of Transplantation at the Columbia University Medical Center Dr. Emond’s activities foster clinical excellence and research across all 11 of the solid organ transplant programs at the Medical Center. In recognition of his national and international leadership in transplantation, Dr. Emond is the President-elect of the American Society of Transplant Surgeons, the pre-eminent association of a transplant surgery.
Contribution to Science
Living donor liver transplantation
Dr. Emond has spent a substantial portion of his career developing living donor liver transplantation and studying the safety of the procedure in both the donor and recipient. He participated in the first living donor liver transplant in the United States and focused on refining the techniques of performing living donor liver transplants and split liver transplants. He was also PI of the NIH-sponsored Adult-to-Adult Living Donor Liver Transplantation (A2ALL) consortium to study the safety and outcomes of living donor liver transplants.
Dr. Emond developed techniques for surgical resection of liver tumors and studied the effect of ischemia during resection on postoperative liver function. These studies include the outcomes of the extent of hepatectomy, the biochemical response to major hepatectomy and ischemia-reperfusion injury of the liver in rodent models. He has studied the clinical safety of inducing total vascular exclusion to provide a bloodless field during the liver transection. This has applications in both liver cancer and living donor hepatectomies.
Hepatocellular carcinoma treatment
Dr. Emond has studied many aspects of managing patients with hepatocellular carcinoma. These studies have included characterizing the risk factors for recurrence of disease following transplantation due to comorbidities and tumor characteristics. The research team has also studied the optimal method of preventing tumor growth in patients with HCC on the liver transplant wait list in addition to optimal strategies of liver allocation to optimize outcomes following liver transplantation. These studies have contributed to proposed changes in UNOS exception point allocation for liver transplant candidates with HCC.
Pediatric liver transplantation
Dr. Emond helped develop the field of pediatric liver transplantation. Contributions to this field include: the use of living donors for pediatric patients; use of auxiliary liver transplants for metabolic diseases; use of partial liver grafts for pediatric patients; and technical modifications that improved outcomes for this patient population.
Education & Training
- University of Chicago Pritzker School of Medicine
- Internship: Cook County Hospital, Illinois
- Residency: Cook County Hospital, Illinois
- Fellowship: Hospital de Paris - France
Committees / Societies / Memberships
- American Association for the Study of Liver Diseases
- American College of Surgeons
- American Society of Hepato-Pancreato-Biliary Surgery
- American Society of Transplant Surgeons
- American Surgical Association
- Association for Academic Surgery
- Compagnons Hepato-Biliaires
- Howard C. Naffziger Surgical Society
- International Hepato-Biliary Pancreatic Association
- International Liver Transplantation Society
- Pacific Coast Surgical Association
- San Francisco Surgical Society
- Societé International de Chirurgie
- Society for Surgery of the Alimentary Tract
- Society of University Surgeons
- Warren H. Cole Society
Honors & Awards
- Ray and Joan Kroc Travelling Scholarship
- Eleanor B. Pillsbury Fellowship
- French Government Post-Graduate Scholarship
- Fulbright Travel Grant for International Study
- Andrew Mellon Young Faculty Member
- PEW Scholars Program-University of Chicago nominee
- Honorary Faculty Member AOA
- Named in The Best Doctors in America Woodward/White, Inc.
- Best Doctors in New York (New York Magazine), 2015-2016
- Ellis Island Medal of Honor, 2000
- Doctor of the Year, Latino Organization for liver awareness, 2000
INCREASING MINORITY POPULATION AWARENESS THROUGH COMMUNITY TEACHING FOR IMPROVED ORGAN DONATION (IMPACT FOR IMPROVED ORGAN DONATION) (Federal Gov)
Aug 1 2017 - May 31 2022
A 24 MONTH, RANDOMIZED, CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CONCENTRATION- CONTROLLED EVEROLIMUS PLUS REDUCED TACROLIMUS IN RECIPIENTS OF LIVING DONOR LIVER TRANSPLANTS (P&S Industry Clinical Trial)
Apr 17 2014 - Apr 17 2019
SOFOSBUVIR AND LEDIPASVIR IN HIV/HCV COINFECTED PRE & POST LIVER TRANSPLANT (Federal Gov)
Jan 15 2015 - Dec 31 2017
IMMUNE TOLERANCE NETWORK (Federal Gov)
Feb 1 2015 - Jun 30 2016
ADULT TO ADULT LIVING DONOR LIVER TRANSPLANTATION COHORT STUDY (Federal Gov)
Sep 1 2002 - Aug 31 2015
2015 ASTS PRESIDENTIAL STUDENT MENTOR GRANT-ANNA YEGIANTS (Private)
May 26 2015 - Aug 28 2015
MOLECULAR PROFILING AND IMMUNOMODULATORY INTERVENTION (Federal Gov)
Sep 1 2007 - Aug 31 2011
MOLECULAR PROFILING AND IMMUNOMODULATORY INTERVENTION (Federal Gov)
Sep 1 2007 - Aug 31 2011
- Rudow DL, Brown RS Jr, Emond JC, Marratta D, Bellemare S, Kinkhabwala M. One-year morbidity after donor right hepatectomy.Liver Transpl. 2004 Nov;10(11):1428-31.
- Russo MW, Lapointe-Rudow D, Teixeira A, Guarrera J, Dove LD, Gaglio P, Emond JC, Kinkhabwala M, Brown RS. Interpretation of Liver Chemistries in Adult Donors After Living Donor Liver Transplantation. J Clin Gastroenterol. 2004 Oct;38(9):810-4.
- Akinlolu O. Ojo, Dennis Heinrichs, Jean C. Emond, Joshua J. McGowan, Mary K. Guidinger, Francis L. Delmonico, Robert A. Metzger. Organ Donation and Utilization in the United States AmJ Transplantation 2004 4(Supp 9):27-37.
- Renz JF, Emond JC, Yersiz H, Ascher NL, Busuttil RW. Split liver transplantation in the United States: Outcomes of a national survey. Ann Surg. 2004 Feb;239(2):172-81.
- Mark W. Russo, Dianne LaPointe-Rudow, Milan Kinkhabwala, Jean Emond, Robert S. Brown. Impact of adult living donor liver transplantation on waiting time survival in candidates listed for liver transplantation. Am J Transplantation 2004 Mar;4(3):427-31.
- Shan Zeng, Nikki Feirt, Michael Goldstein1, James Guarrera1, Udeme Ekong, Yan Lu, Wu Qu, Ann Marie Schmidt and Jean C. Emond. Blockade of the receptor for AGE (RAGE) attenuates ischemia and reperfusion injury to the liver in mice. Hepatology 2004 39:422-432.
- Paul J. Gaglio, Srikar Malireddy, Brian S. Levitt, Dianne Lapointe-Rudow, Jay Lefkowitch, Milan Kinkhabwala, Mark W. Russo, Jean C Emond, and Robert S. Brown, Jr. Increased risk of cholestatic hepatitis C in recipients of grafts from living versus cadaveric liver donors. Liver Transpl. 2003 Oct;9(10):1028-35.
- Kinkhabwala MM, Guarrera JV, Leno R, Brown RS, Prowda J, Kapur S, Emond JC. Outflow reconstruction in right hepatic live donor liver transplantation. Surgery 2003 Mar;133(3):243-50
- Rudow DL, Russo MW, Hafliger S, Emond JC, Brown RS Jr. Clinical and ethnic differences in candidates listed for liver transplantation with and without potential living donors. Liver Transpl 2003 Mar;9(3):254-9
- Michael J. Goldstein, Sandip Kapur, Milan Kinkhabwala, Patricia Harren, Diane LaPoint-Rudow, Steven J. Lobritto, Mark Russo, Robert S. Brown, Jr., Alan Weinberg, John F. Renz, Jean C. Emond. Analysis of failure in living donor liver transplants: Differential outcomes in adults and children. World J Surg. 2003 Mar;27(3):356-64.
- Bruce R. Rosengard,. Sandy Feng,. Edward J. Alfrey, Jon Zaroff, Jean C. Emond, Mitchell L. Henry,. Edward R. Garrity, John P. Roberts, James J. Wynn, Robert A. Metzger, Richard B. Freeman, Friedrich K. Port, Robert B. Love, Ronald W. Busuttil, Francis L. Delmonico. Report of the Crystal City Meeting To Maximize the Use of Organs Recovered from the Cadaver Donor AmJ Transplantation 2002 Sep;2(8):701-11
- Jean C. Emond, Richard B. Freeman Jr, John F. Renz2, Xavier Rogiers, Ronald W. Busuttil. Optimizing the use of donated cadaver livers: Analysis and policy development to increase the use of split livers. Liver Transpl. 2002 Oct;8(10):863-72.
- Salame E, Soauf R, Kinkhabwala M, Harren P, Finn R, Brown RS, Emond JC. Impact of the extent of hepatectomy on donor outcomes:liver function and clinical recovery after living donor liver transplantation. Am J Transplant. 2002 Sep;2(8):780-8.
- Diaz GC, Renz JF, Mudge C, Roberts JP, Ascher NL, Emond JC, Rosenthal P. Donor health assessment following living-donor transplantation. Ann Surg 236(1):120-126, 2002.
- Robert S. Brown, Jr., K. Shiva Kumar, Steven J. Lobritto, Dianne L. Rudow, Patricia Harren, Milan Kinkhabwala, Sandip Kapur, Jean C. Emond. Comparison of May end-stage liver disease (MELD) scores and Child-Turcotte-Pugh (CPT) scores as predictors of pre liver transplant (LT) disease severity and post-LT outcomes in UNOS status 2A patients. Liver Transpl. 2002 Mar;8(3):278-84.
- Renz JF, DeRoos M, Rosenthal P, Mudge C, Bacchetti P, Watson J, Roberts JP, Ascher NL, Emond JC. Post-transplantation growth in pediatric liver recipients. Liver Transpl 2001 Dec;7(12):1040-55
- Renz JF, Reichert PR, Emond JC. Biliary anatomy as applied to pediatric living donor and split-liver transplantation. Liver Transpl 2000 Nov;6(6):801-4.
- Emond JC, De Luca T. Il trapianto di fegato da familiare vivente: selezione di riciventi e donatori Minerva Chir 2000 Nov;55(11):759-69
- Dower NA, Smith LJ, Lees G, Kneteman N, Idikio H, Emond J, Rosenthal P. Experience with aggressive therapy in three children with unresectable malignant liver tumors. Med Pediatr Oncol. 2000 Feb;34(2):132-5.
- Renz JF, Reichert PR, Emond JC. Hepatic arterial anatomy as applied to living-donor and split-liver transplantation. Liver Transpl 2000 May;6(3):367-9.
Book Chapters, Reviews, And Editorials
- Forman LM, Trotter JF, Emond J. Living donor liver transplantation and hepatitis C (Editorial). Liver Transpl. 2004 Mar;10(3):347-348.
- Emond JC. Living donor liver transplantation in children: what to recommend? (Editorial) Am. J. Transplantation 2004 Mar;4(3):293-4.
- Renz JF, Yersiz H, Reichert PR, Hisatake GM, Farmer DG, Ghobrial RM, Emond JC, Bussuttil RW. Split-Liver Transplantation: A Review. Am. J. Transplantation 2003; 3:1-13.
- Haskal ZJ, Emond J, Brown R. Mesenteric venous thrombosis. N Engl J M 2002; 346: 1252.(Letter).
- Emond JC. What’s new in transplantation 2002. J Am Coll Surg. 2002 May;194(5):636-41.
- Guarrera JV and Emond JC. Advances in segmental liver transplantation: Can we solve the donor shortage? Transplant Proc. 2001 Nov;33(7-8):3451-5.
- Emond JC. Optimizing the donor pool: The status of split liver and living donor liver transplants 2001. in Eds: Arroyo V et al. “Therapy in Hepatology” Ars Medica Spain 2001:317-323.
- Samstein B, Emond J. Liver transplants from living related donors. Annu Rev Med 2001;52:147-60
- Rosenthal J, Sussman J, Haskall Z Emond JC. Transjugular intrahepatic portosystemic shunts. In: ed: Cameron JL. “Current Surgical Therapy” 7th edition. Mosby 2001:399-406.
- Marvin M and Emond JC. Cirrhosis and portal hypertension in: ed: Greenfield LJ. “ Surgery: Scientific Principles and Practice” Lippincott Williams and Wilkins 2001: 957-988.